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Ambien 10mg (zolpidem tartrate) requires a valid prescription from a DEA-registered US healthcare provider as a Schedule IV controlled substance for short-term insomnia treatment when difficulty falling asleep persists; no secure after-hours shipping or online service can legally dispense it without thorough medical evaluation, and prescription-free purchases constitute federal felony distribution under 21 U.S.C. § 841.
The 10mg immediate-release dose serves as maximum for men (women/elderly start 5mg) taken once nightly with 7-8 hours sleep opportunity, limited to 7-10 days max under 2025 DEA telemedicine (ends 12/31/2025), requiring HIPAA video with ISI>14 confirming DSM-5 insomnia, excluding OSA (STOP-BANG<3), depression (PHQ-9<10), SUD (DAST<2), and CBT-I failure—no "shipping" bypasses EPCS or post-2025 in-person mandates.
α1-selective agonist (Ki 25nM), Tmax 1.6h, t½ 2.5h; women 5mg (AUC 30-50% higher); contraindications: sleep apnea, myasthenia, severe liver; black box: complex sleep behaviors (sleep-driving 0.1-1%), next-day impairment (4x crash risk 10mg women), dependence (15% high-dose)—discontinue on behaviors.
ISI≥15 + sleep diary.
Video (PDMP/STOP<3).
Consent (10-20% behaviors).
EPCS #30 tabs men.
C-IV signature delivery.
Day 7 check (>30min SOL reduction).
| Rate | Effects | Management |
|---|---|---|
| ≥10% | Drowsiness (8%) | 5mg women, 7h sleep |
| 1-5% | Headache (7%) | Transient |
| 0.1-1% | Sleep-driving | Immediate DC |
| <0.1% | Falls elderly | 5mg max |
Overdose: flumazenil cautious; CYP3A4i x2 AUC.
| Tier | Therapy | SOL ↓ | Duration |
|---|---|---|---|
| 1 | CBT-I 6-8 sess | 50% | Sustained |
| 2 | Hygiene/stimulus | 30% | Immediate |
| 3 | Melatonin 3mg | 20min | Chronic |
Ambien 10mg no Rx legal? No—Schedule IV felony.
Women dose? 5mg max.