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 Percocet remains an important option in modern pain management when other therapies are insufficient. The medication combines oxycodone and acetaminophen and is available in 325 mg, 500 mg, and 650 mg tablet strengths to accommodate varying levels of pain severity. It is primarily prescribed for short-term use in conditions such as post-surgical recovery, severe back pain, gallstones, or acute abdominal discomfort. Oxycodone reduces pain perception in the brain and spinal cord, while acetaminophen enhances analgesic effects and targets inflammation. Because Percocet contains an opioid, strict adherence to prescribed dosages and monitoring by healthcare providers is essential to prevent dependence, misuse, or side effects. Patients may experience common adverse effects such as drowsiness, dizziness, constipation, or nausea, and serious complications, although rare, require immediate medical attention. Physicians often integrate Percocet into a comprehensive pain management plan that may include non-opioid alternatives, physical therapy, and lifestyle adjustments to optimize results. Patient education focuses on safe use, potential side effects, and proper storage and disposal. By following clinical guidance and using Percocet responsibly, patients can benefit from meaningful pain relief while minimizing risks associated with opioid medications.